Histopathologic image of clear cell carcinoma of the kidney, nephrectomy specimen; source: KGH, Wikimedia Commons (cancernetwork.com)
Researchers led by Van Allen and Choueiri sought an explanation for why some patients with a form of metastatic kidney cancer called clear cell renal cell cancer (ccRCC) gain clinical benefit — sometimes durable — from treatment with immune checkpoint inhibitors that block the PD - 1 checkpoint, while other patients don't. (sciencedaily.com)
Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. (jcancer.org)