I had this multiple times and I had to restart entire levels. (lifeisxbox.eu)
There were entire levels of Torchlight II (shown above — sans roaches) that I simply couldn't play until some lovely modder came up with a plugin to get rid of them after many players begged him to. (massivelyop.com)
Naughty Dog could have simply crafted a cutscene for the train sequence of Uncharted 2 — instead, they designed two entire levels in which the player was forced to traverse it himself. (riddlethos.com)