Coordinated by the UK Cystic Fibrosis Gene Therapy Consortium, the two - year study involved 136 CF patients aged 12 years or older from across the UK. (sciencedaily.com)
The current U.K. trial is again using fats, or lipids, but the DNA includes a segment called a promoter that should make gene expression last longer, says Eric Alton of Imperial College London, who heads the UK Cystic Fibrosis Gene Therapy Consortium. (sciencemag.org)
It is most commonly caused by a mutation in the cystic fibrosis gene known as F508del. (sciencedaily.com)