The UK patents relate to the CRISPR - Cas9 gene editing systems involving single - guide RNA in both non-cellular and cellular settings (UK Patent No. 2518764) and chimeric CRISPR - Cas9 systems in which the Cas9 protein is modified to provide alternative DNA - modulating activities (UK Patent No. 2537000). (cariboubio.com)
«The insights gained from the intensive use of insecticides and its impact on the mosquito genome will be critical for the successful implementation of gene editing systems as a new approach to controlling mosquito - borne diseases,» Kamdem said. (sciencedaily.com)
«Patients» individual genomes may affect efficacy, safety of gene editing: CRISPR - Cas9 and other gene editing systems may need to be customized to the patient.» (sciencedaily.com)