Journal of Molecular Endocrinology, 2004, 33:797 - 803, «High glucose decreases intracellular glutathione concentrations and upregulates inducible nitric oxide synthase gene expression in intestinal epithelial cells» (fullhealthsecrets.com)
Given the importance of ATP synthase in fueling the cell, determining the complete structure of the enzyme has been a scientific holy grail, promising to reveal secrets about the ATP machine that could lead to therapeutic target identification and advance understanding of metabolic disease and other cellular pathologies. (sciencedaily.com)
In particular, chemical inhibitors of glycogen synthase kinase 3 (GSK - 3) were found to elevate SMN levels by stabilizing the protein. (smafoundation.org)