Definition of «microglial»

Microglia are a type of cell found in the central nervous system, specifically within the brain and spinal cord. They are part of the immune system and play an important role in maintaining the health of the nervous system by monitoring for any damage or injury to neurons. Microglia act as the first responders to such events and help to clear away debris from injured areas, release cytokines to recruit other immune cells, and initiate a healing process. They also play a role in synaptic pruning during development and have been implicated in various neurological disorders including Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

Sentences with «microglial»

  • Patients with major depressive disorder (MDD) have increased brain levels of a marker of microglial activation, a sign of inflammation, according to a new study in Biological Psychiatry by researchers at the University of Manchester, United Kingdom. (sciencedaily.com)
  • Since the recent discovery of microglial function in the 1990's, they have become the focus how the brain responds and recovered from injury. (onnit.com)
  • They found increased microglial activity in both those who had schizophrenia, and those who had been classified as ultra-high risk. (newscientist.com)
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