In simpler terms, "plasma homocysteine" refers to a substance called homocysteine that is found in our blood. Homocysteine levels can sometimes be used as a marker to measure the risk of certain health problems, such as heart disease.
In a sample of 1,092 men and women without dementia followed for an average of 10 years, those with higher plasma homocysteine levels at baseline had a significantly higher risk of developing Alzheimer's disease and other types of dementia. (lpi.oregonstate.edu)
Inadequate dietary intake of methyl groups leads to hypomethylation in many important pathways, including 1) disturbed hepatic protein (methionine) metabolism as determined by elevated plasma homocysteine concentrations and decreased S - adenosylmethionine concentrations, and 2) inadequate hepatic fat metabolism, which leads to steatosis (fatty accumulation) and subsequent plasma dyslipidemia. (academic.oup.com)
Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism. (progressivehealth.com)