Definition of «senescence»

Senescence refers to the process of aging or growing old. It is a state in which an organism, cell, or tissue loses its ability to function properly due to the passage of time and the accumulation of damage. Senescence can occur at different levels, such as cellular senescence (where cells lose their ability to divide), tissue senescence (where organs or tissues lose their functionality), and organismal senescence (where the entire organism experiences a decline in its abilities). The process of senescence is influenced by various factors, including genetics, environmental stressors, and cellular damage.

Sentences with «senescence»

  • This may well be more a sign of the times, a measure of the increasing interest in the research community directed towards the role of cellular senescence in aging, rather than something that arises organically. (fightaging.org)
  • Again, then, there is significant evidence consistent with a role of cellular senescence in age - related lipodystrophy and lipoatrophy, and for the benefits observed in treated mice in these studies to translate into aging humans. (sens.org)
  • Cardiovascular disease and renal disease for example are accelerated in patients with diabetes and AGEs have been shown to induce senescence in cell types related to these diseases, such as endothelial progenitor cells, vascular endothelial cells and renal cells. (fightaging.org)
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