The phrase "active enhancers" refers to things that make something better or stronger. It means things or factors that improve or boost the performance or effectiveness of something. Full definition
Then for HARE5, the most active enhancer in an area of the brain called the cortex, they made minigenes containing either the chimp or human version of the enhancer linked to a «reporter» gene that caused the developing mouse embryo to turn blue wherever the enhancer turned the gene on. (sciencemag.org)
By studying recurrent somatic SVs affecting intergenic regions, we recently demonstrated that «enhancer hijacking» — the juxtaposition of active enhancers near proto - oncogenes, and often across topological association domain (TAD) boundaries — is a frequent oncogene activation mechanism in solid tumors (Figure 2). (embl.de)
In Class II engagement, Sox9 binds to multiple active enhancer elements through sub-optimal, low - affinity Sox dimeric motifs (DNA sequences), resulting in a high level of transcription of cartilage - related genes. (sciencedaily.com)