Primary cancer affects certain organ, and then spreads to adjacent tissues in secondary or latter stages. (dog-health-handbook.com)
The tumors can spread locally, affecting adjacent tissues, but long term, if left untreated, it can spread to distant areas like lymph nodes or lung tissue. (cathealth.com)
Despite the similar ability of transplanted hGDAsBMP and hGDAsCNTF to span the rostral to caudal extent of injury sites and migrate into adjacent tissues, only hGDAsBMP promoted locomotor recovery following transplantation into the transected dorsolateral funiculus (DLF). (journals.plos.org)