The drug resulted in greater than 80 percent decrease in growth of adrenal cancer cell lines as well as inhibition of tumor growth in animal models. (coloradocancerblogs.org)
«Researchers have done metabolic studies in patients with adrenal cancer, but they have looked at larger molecules, and they have targeted their investigations at specific steroids or gene profiles. (sciencedaily.com)
To discover new promising treatments, the group mined publicly available data from the Cancer Genome Atlas (TCGA) and found a 12-fold increase in the expression of the «kinase» PBK in adrenal cancers compared with healthy adrenal tissue. (coloradocancerblogs.org)