This low speed may make it vulnerable to sophisticated air defense systems Russia is known for such as its advanced S - 400 system, called the SA - 21 Growler in the west. (businessinsider.com)
Russia did not respond during the strike with its advanced air defense systems on the ground in Syria. (politics.stackexchange.com)
However, the low altitude flight profile of an attacking Tomahawk, its ability to use terrain masking for cover and concealment and its relatively small size, significantly smaller than a manned combat aircraft, make it a difficult target for even the most advanced air defense systems. (businessinsider.com)