In alkaline conditions in the scalp however, the enzyme is inhibited, meaning, naturally, it doesn't work very well. (hairlossrevolution.com)
Here, they demonstrate that the worms are averse to a very high pH by showing that the worms avoided areas of the experimental environment where the researchers created highly alkaline conditions. (sciencedaily.com)
Some nuclear waste contains cellulose, which can break down to form isosaccharinic acid (ISA) under alkaline conditions. (newscientist.com)