Estimation of 2Nes from temporal allele frequency data Bollback, J. P., T. L. York, and R. Nielsen. (nielsenlab.org)
Thus, while the mere presence of a variant in dbSNP is a blunt tool for variant filtering, dbSNP's deep allele frequency data make it incredibly powerful for genetics studies: it can rule out variants that are too prevalent to be disease - causing, and prioritize ones that are rarely observed in human populations. (massgenomics.org)
Pickrell, J. K. & Pritchard, J. K. Inference of population splits and mixtures from genome - wide allele frequency data. (nature.com)