Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: a systematic review and meta - anlaysis of observational studies. (empoweredautoimmune.com)
The metabolic analysis of the mice could be combined with clinical assessments, by performing biochemical analysis in blood, plasma, urine and tissues (i.e, lipid and cholesterol content, glycogen content...) and by performing autopsy of the animal at the end of phenotyping study with several tissue collections (i.e, histology, mRNA anlaysis, protein analysis...). (ics-mci.fr)