The article reviews current literature on the use of adoptive immunotherapy for malignant gliomas as well as the the concept of antitumor activity mediated by CIK cells. (neuro-central.com)
Dr. Sharma is the principal investigator of multiple immunotherapy trials and performs extensive laboratory studies on patients» samples to gain insights regarding mechanisms and pathways involved in antitumor responses. (sciencemag.org)
Mechanistic studies showed that IFN increases antitumor immune responses by enhancing antigen presentation to T cells by dendritic cells present in the tumor microenvironment. (science.sciencemag.org)