They then looked to see what amino acids were inserted when ataluren allowed a skip - over of the premature nonsense mutation. (sciencedaily.com)
Today's communication maps out a few paths forward and with those paths come continued hope for an eventual approval of ataluren in the U.S. PPMD will work with PTC, doing what we can to support them while they develop a plan to collect the data the FDA has requested. (parentprojectmd.org)
In a paper in the Proceedings of the National Academy of Sciences, they report that ataluren acts at the ribosome, and it allows the insertion of amino acids that are similar to the ones that would have been present in the nonmutated gene. (sciencedaily.com)