First, an unacceptable side effect profile of killed bacterial vaccines has often been reported. (dogsnaturallymagazine.com)
Like most bacterial vaccines, it requires two shots to be of any use; it does not produce long - lasting immunity; and it carries a higher risk of adverse reactions. (littlebigcat.com)
Bacterial vaccines for dogs are bordetella, leptospirosis, and Lyme disease. (caberfeidh.com)