Colonies # 4, # 16 and # 22 carry biallelic mutations of MSTN. (journals.plos.org)
In the third type of biallelic effect, known as interallelic complementation, two mutant alleles produced a phenotype closer to wt than either could alone in a homo - or hemizygous state. (journals.plos.org)
In this study, we demonstrate for the first time that Cas9 / gRNA - mediated gene knockout approach is highly efficient in goats resulting in successful generation of cloned goats with biallelic mutations. (journals.plos.org)