Reducing vitamin B12 levels in bone cells in the laboratory did not affect the function of the bone - forming cells directly, while under the same conditions it affected liver cell functions profoundly. (sciencedaily.com)
The team is also working on new study methods that may enable them to test the new drug in the lab on small samples of bone cells taken from patients. (sciencedaily.com)
They then used human stem cells derived from bone marrow that would normally become bone cells to test the effects of the nanoparticles on stem cell proliferation and differentiation. (sciencedaily.com)