Exclusion criteria were: lymphoma outside the CNS, HIV positivity, inadequate bone marrow function, liver disease, creatinine clearance less than 60 mL / min, organ transplantation, prior radiotherapy to the brain, previous malignancy unless disease free for at least five years, pregnancy or lactation. (haematologica.org)
CBC (complete blood count) / differential obtained within 14 days prior, with adequate bone marrow function defined as follows: (clinicaltrials.gov)
A patient receives intensive chemotherapy with or without total body irradiation therapy in an attempt to kill all cancerous cells, but which also destroy his / her own bone marrow function. (cityofhope.org)