Tiziana Life Sciences was founded in 2014 after licencing the BCL3 cancer agent that was developed by the same Cardiff University team. (sciencedaily.com)
Moreover, experimental cancer agents are usually tested in patients who have already received several prior therapies, which blunt the immune system, Schlom remarks. (scientificamerican.com)
A similar antibody - drug conjugate approach is used by the breast cancer agent T - DM1, which attaches chemotherapy to an antibody that seeks the HER2 protein in HER2 + breast cancers. (sciencedaily.com)