We have developed a sequencing based approach to show similar in human tissues, finding around a third of cells in normal sun exposed facial skin carry cancer driver gene mutations. (sanger.ac.uk)
She is particularly interested in the identification of cancer driver mutations, genes and pathways across tumor types and in the study of their targeted opportunities. (irbbarcelona.org)
Some of these genes are big cancer drivers in adults yet haven't historically been tied to childhood disease. (sciencemag.org)