Target - based strategies typically employ in vitro high - throughput screening methods to identify small molecules that alter the activity of an identified candidate protein implicated in a disease process. (mdibl.org)
«Application of Proteomics in the Discovery of Candidate Protein Biomarkers in a Diabetes Autoantibody Standardization Program Sample Subset.» (pnnl.gov)
Klemke's laboratory has already identified several candidate proteins using this technique that may be key players in pseudopod formation and cell movement. (scripps.edu)