They demonstrated that reducing the effects of the protein FASN influences the mitochondria, leading to increased cardiolipin levels and reduced Parkinson's symptoms. (sciencedaily.com)
Using standard enzyme - linked immunosorbent assays (ELISA) and peripheral blood mononuclear cell (PBMC) assays, researchers discovered that unlike previously described human antibodies to lipids, WR321 did not react with any of 17 other lipids it was tested against, including cholesterol, glycolipids, and other phospholipids such as cardiolipin and phosphatidylserine, but it bound specifically only to two phosphoinositides. (hivresearch.org)
Prof. Patrik Verstreken (VIB - KU Leuven): «The PINK1 gene encodes the PINK1 protein, and mutations in it lead to lower levels of cardiolipin in mitochondria. (sciencedaily.com)