These genes are associated with these traits through SNPs, which may be located in intergenic regions, and they do not need to have functional evidence as causal genes for obesity or T2D. (diabetes.diabetesjournals.org)
The team pares down a list of about 500 likely causal genes to slightly more than 200 best «candidate» autism genes. (sciencedaily.com)
These studies are unable to determine a causal relationship due to factors such as gene regulation — a genetic variant may instead contribute to altered expression levels of true causal genes, which remain undetected by a GWAS. (uchospitals.edu)