Because of its hard to develop for cell architecture. (fgindex.com)
I think a lot of people really don't understand cell architecture to know why it was ahead if it's time, and extremely powerful for the way game design was going. (n4g.com)
The Chips are cultured under continuous flow within engineered 3D microenvironments that go beyond conventional 3D in vitro models by recapitulating in vivo intercellular interactions, spatiotemporal gradients, vascular perfusion, and mechanical forces — all key drivers of cell architecture, differentiated function, and gene expression. (emulatebio.com)