HNF -1-alpha and HNF -4-alpha are members of a regulatory pathway first identified in cells of the liver but present in other cells including those of the kidney and intestine. (uchospitals.edu)
While the T cells of the liver transplant recipients reacted to the donor organ cells weakly, their reaction to other antigens was preserved. (sciencedaily.com)
Even in nanomedicine, which is one of the best new methods for delivering drugs to a tumor, only about one percent of a dose of nanoparticles will successfully arrive at the intended tumor site, while the rest are filtered out by the immune cells of the liver and spleen. (sciencedaily.com)