Our initial comparative analysis - performed on library of 19 C. elegans models (including 7 models for human muscular dystrophies)- suggested the existence of some shared cellular consequences to various primary genetic defects causing muscle degeneration. (inmg.fr)
Although the metabolic responses observed are consistent with the cellular consequences of osteocalcin exposure in pancreatic β - cells and myoblasts in vitro (27 — 29, 61), the metabolic effects of exercise and WBV may not be dependent on osteocalcin per se. (academic.oup.com)
In October, Jonathan Weissman's lab introduced additional pooled CRISPR libraries, also available at Addgene, enabling systematic investigation of the cellular consequences of repressing or inducing individual transcripts. (blog.addgene.org)