Although certain nerve endings throughout the body can indeed detect bodily harm, their signals are only one factor that the brain uses to determine if we should experience pain. (scientificamerican.com)
To do this, the surgeon will cut or destroy certain nerves. (aad.org)
Researchers from University of Utah Health show that eliminating the gene encoding Lef1 disrupts the development of certain nerve cells in the hypothalamus that affect stress and anxiety. (sciencedaily.com)