Phrases with «checkpoint blockade»

"Checkpoint blockade" is a term used in the field of immunology to describe a mechanism that allows the immune system to block certain checkpoints or signals that prevent it from attacking cancer cells. By lifting these barriers, the immune system becomes better equipped to recognize and kill cancer cells, promoting the body's ability to fight against cancer. Full definition

checkpoint blockade

immune checkpoint blockade

Sentences with «checkpoint blockade»

Researchers at The University of Texas MD Anderson Cancer Center developed a novel chimeric mouse model to test the combination therapy using immune checkpoint blockades with therapies targeting myeloid - derived suppressor cells (MDSCs). (sciencedaily.com)
Some of the most dramatic clinical responses seen in recent years have occurred with checkpoint blockade antibodies, including ipilimumab (anti-CTLA-4) and nivolumab (anti-PD-1). (cancerresearch.org)
In a retrospective analysis of clinical trial data, they found that melanoma patients with highly aneuploid tumors were less likely to benefit from immune checkpoint blockade therapy than patients whose tumors showed fewer chromosomal disruptions. (sciencedaily.com)
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Phrases with «checkpoint blockade»

Sentences with «checkpoint blockade»

See also