Researchers at The University of Texas MD Anderson Cancer Center developed a novel chimeric mouse model to test the combination therapy using immune checkpoint blockades with therapies targeting myeloid - derived suppressor cells (MDSCs). (sciencedaily.com)
The CD31 antibody - reactive cells (red, A and E) and AFP antibody - reactive cells (red, I and M) were detected specifically in the liver of chimeric mice from iPS cells of line 11.1. (journals.plos.org)
Allogenic allografts in chimeric mice were harvested on either day 40 or day 100 - post transplantation. (journals.plos.org)