What are the characteristics of the putative chondrogenic progenitor, and can we use these to create a purer, and more effective, cell population? (stemcellsportal.com)
Their gene expression analysis throughout the protocol matched that of a previously published profile for hESCs [24], which included the significant upregulation of mesodermal and chondrogenic markers (PDGFRB, SOX6, SOX9, ACAN, COL2A1 types A and B), with the more mature COL2A1 type B splice variant [42] being more highly expressed by the end of stage 3. (stemcellsportal.com)
His research interests include the mechano - regulation of stem cell fate, in particular chondrogenic differentiation. (sciencemag.org)