«We discovered that when memory CD4 T cells were induced in the absence of antiviral CD8 responses or antibodies, they triggered an overwhelming inflammatory response in a mouse model of lymphocytic choriomeningitis virus [LCMV] infection,» explains senior author Dan Barouch, MD, PhD, director of the Center for Virology and Vaccine Research at BIDMC and Professor of Medicine at Harvard Medical School (HMS). (sciencedaily.com)
Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. (immunohorizons.org)
Platelets prevent IFN - a / b - induced lethal hemorrhage promoting CTL - dependent clearance of lymphocytic choriomeningitis virus. (research.hsr.it)