Phrases with «chromatin modifiers»

"Chromatin modifiers" refers to certain substances or proteins that can make changes to the structure or arrangement of the DNA and proteins that make up the chromatin in our cells. These modifications can affect the activity and expression of genes, influencing various cellular processes and functions. Full definition

Sentences with «chromatin modifiers»

  • Our lab is focused on understanding the effects of chromatin modifier mutations on the initiation and progression of urothelial cancers of the bladder and upper tract. (lerner.ccf.org)
  • One type of chromatin modifiers is called histone deacetylase (HDAC), of which 18 variants are known in humans. (sciencedaily.com)
  • We are investigating how chromatin modifier mutations act to promote urothelial cancer development and potentially render these cancers susceptible to novel drug combinations. (lerner.ccf.org)
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