Furthermore, TP63 has been implicated in human NSCL / P [44], and null mice recapitulate the human orofacial clefting phenotypes [45]. (journals.plos.org)
Heterozygous mutations in human TP63 are associated with a number of allelic syndromes characterized by orofacial defects, including Ectrodactyly - Ectodermal dysplasia - Cleft lip / palate and Ankyloblepharon - Ectodermal dysplasia - Clefting [43]. (journals.plos.org)
Other times when a mom may pump due to a baby's medical condition would be when baby has some kind of lip or palate clefting or muscle tone issue that is not able to be resolved with accommodations. (verywellfamily.com)