He has published seminal works on blood pressure management through his role in the BPLTTC and played leading roles in a series of trials that define the clinical management of patients with diabetes and chronic kidney disease. (sydney.edu.au)
In this special section of Science, expert contributors retrace the long and tortuous path leading to the mapping and identification of the BRCA1 gene; discuss the ways in which BRCA mutation status has been integrated into the clinical management of patients in high - risk families; and highlight the role of the BRCA proteins in preserving the structural and numerical integrity of chromosomes throughout the cell cycle, a function that may explain their tumor suppressor activity. (science.sciencemag.org)
«This discovery demonstrates that it's possible for clinical research to have a big impact on diagnostics for patients with undiagnosed disease and influence the clinical management of patients and family members,» said study author Dana Vuzman, PhD, co-director of the Brigham Genomic Medicine Program. (sciencedaily.com)