The advantage to buying 1 of their puppies is that they test their dogs for common genetic diseases. (dogbreedz.com)
Alpha -1-antitrypsin deficiency (A1ATD) is the most common genetic disease of the liver, and is caused by a single nucleotide change in the gene that codes for alpha -1-antitrypsin (A1AT), an enzyme inhibitor that normally protects bodily tissues. (scientificamerican.com)
Since they do not source pets from parents that have undergone basic genetic testing before breeding (as all veterinarians strongly recommend), even common genetic diseases flourish among these purebreds. (petsmagazine.com.sg)