This is particularly relevant given that isoform - selective inhibitors are likely to exhibit lower toxicity compared to generic inhibitors, and therefore higher drug doses that are capable of achieving complete inhibition of the pathway may be tolerated. (sciencedaily.com)
Immunoblots showed almost complete inhibition of mTOR expression (as shown in Fig. 4B) that resulted in decreased cell proliferation as assessed by MTS assay (A). (cancerres.aacrjournals.org)
The active compounds in honey (such as Methylglyoxal) are present in the matrix of honey and a more concentrated honey would be required for complete inhibition. (berringa.com)