Globally, it is one of the leading clinical research centers for rheumatoid arthritis, systemic connective tissue disorders (such as lupus erythematosus, Sjögren's syndrome, and scleroderma), as well as inflammatory musculoskeletal and vascular disorders. (charite.de)
Celiac disease is associated frequently with iron deficiency anemia, dermatitis herpetiformis, selective IgA deficiency, thyroid disorders, diabetes mellitus, and various connective tissue disorders but is rarely associated with cardiomyopathy. (naturalmedicine101.com)
In order to lengthen a muscle the time a stretch must be held will vary depending on age, fitness level, prior injuries, and other systemic conditions (i.e. connective tissue disorders, autoimmune disorders, etc..) (stretching-exercises-guide.com)