Studies the genetics of degenerative muscle diseases using mouse models for SMA, ALS, muscular dystrophy and more. (jax.org)
We are also studying mice with degenerative muscle diseases that are models for specific forms of muscular dystrophy in humans. (jax.org)
While transplantation of such muscle stem cells can be a potent therapy for degenerative muscle diseases such as Duchenne muscular dystrophy, these cells tend to lose their transplantation efficiency when cultured in vitro. (sciencedaily.com)