The authors conclude, «T3 may be considered to ameliorate some of the risk factors associated with abdominal obesity, particularly in some subgroups of obese women with a relative resistance to thyroid hormones possibly dependent on decreased peripheral deiodination of thyroxine (T4)(53).» (holtorfmed.com)
EPA's assay uses cell - derived deiodinase enzymes and measures a chemical's ability to prevent deiodination. (cen.acs.org)
Kohrle J. Thyroid hormone deiodination in target tissues — a regulatory role for the trace element selenium? (progressivehealth.com)