The phrase "deleterious mutations" refers to genetic changes that are harmful or have a negative effect on an organism's health or survival. Full definition
Both genome size and the rate of deleterious mutations in functional parts of the genome have previously been determined, and historical data documents human population levels. (sciencedaily.com)
The observed difference in deleterious mutation loads between ancient and domesticated horses could also reflect the difference in their inbreeding levels (Fig. 4A and SI Appendix, Fig. (pnas.org)
CS is caused by deleterious mutations in SLC9A6, an X-linked gene that codes for the endosomal Na + / H + exchanger 6 (NHE6), which is believed to be involved with circuit development [2, 3]. (jneurodevdisorders.biomedcentral.com)