The phrase "depression issues" refers to problems or difficulties related to depression, which is a mental health condition characterized by persistent sadness, low mood, and lack of interest or pleasure in activities. Full definition
I struggled with addiction and depression issues through high school and early college. (health.com)
With «Daredevil,» it's much more mappable in my head, because I've been no stranger about this, I've dealt with depression issues in the past and stuff, and I still do with that. (cbr.com)
NICHM - Identifying and Treating Maternal Depression This issue brief from National Institute for Health Care Management (NIHCM) provides an comprehensive overview of how to identify and treat maternal depression by offering strategies and considerations for health plans. (2020mom.org)