In addition, animal models show that sufficient magnesium seems to protect the brain from depression and anxiety after traumatic brain injury (6), and that the antidepressants desipramine and St. John's Wort (hypericum perforatum) seem to protect the mice from the toxic effects of magnesium deficiency and its relationship to anxious and depressed behaviors (4). (psychologytoday.com)
Utility of crossover designs in clinical trials: Efficacy of desipramine vs. placebo in opioid - dependent cocaine abusers. (oslc.org)
Curcumin also enhanced the effects of commonly - prescribed antidepressants like fluoxetine (Prozac) and desipramine (Norpramin)(1). (kellybroganmd.com)