More likely, Pascual said, the two work in tandem to an effect greater than the sum of their parts, with rising temperatures leading to faster development of drug resistance. (scientificamerican.com)
The findings, which were demonstrated in several major subtypes of melanoma tumors (including BRAF and NRAS melanoma), could lead to drug development strategies that suppress the development of drug resistance. (sciencedaily.com)
Current treatments require active viral replication and target late stages of infection, which has led to the development of drug resistance. (sciencedaily.com)