(2) This study is consistent with the results of another study in which neutering and spaying was determined to be the most significant gender - associated risk factor for development of hypothyroidism. (chercarkennels.net)
The presence of autoantibody titers against T3 and T4 does not reliably correlate with development of hypothyroidism (not all dogs with autoantibodies develop the disorder) but dogs that are producing autoantibodies are more likely to develop hypothyroidism than dogs without the antibodies. (vetinfo.com)
Vaccination of pet and research dogs with polyvalent vaccines containing rabies virus or rabies vaccine alone was recently shown to induce production of antithyroglobulin autoantibodies, a provocative and important finding with implications for the subsequent development of hypothyroidism (Scott - Moncrieff et al, 2002). (dogsnaturallymagazine.com)