Nutrient imbalances and excesses during growth may lead to developmental orthopedic diseases and subsequent development of osteoarthritis in large - and giant - breed dogs (FIGURE 1). (todaysveterinarynurse.com)
Hip joint laxity as measured by the DI is strongly correlated with the future development of osteoarthritis. (oldenglishsheepdogclubofamerica.org)
When the team administered adenosine packaged in lipid bubbles into rats» ACL injuries, researchers found that the excess adenosine, as mediated by the adenosine A2A receptor, prevented the development of osteoarthritis in the animals. (sciencedaily.com)