I don't take insulin, but I do take the oral diabetes drug metformin twice a day to lower my blood sugar, and I exercise — a lot. (health.com)
One big review of 14 studies found that berberine extracts are equally as effective at lowering insulin as the common diabetes drugs metformin, glipizide, and rosiglitazone. (supernaturalacnetreatment.com)
In particular, the commonly prescribed diabetes drug metformin had positive effects on heart function in women but not in men, who experienced a shift in metabolism thought to increase the risk of heart failure. (source.wustl.edu)