We show that subpopulations of human astrocytes, generated by activation of different signaling pathways in the same population of human glial precursor cells, have markedly different effects when transplanted into the injured spinal cord. (journals.plos.org)
GSK3 (Glycogen Synthase Kinase - 3) is a signaling mediator involved in a variety of different signaling pathways including WNT, growth factors, insulin, and Hedgehog pathways. (ptglab.com)
It plays a role in many different signaling pathways,» says Salk Professor Kuo - Fen Lee, holder of the Helen McLoraine Chair in Molecular Neurobiology and co-senior author of the new work. (sciencedaily.com)